Wen Shan YEW is currently an Associate Professor with the Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore. He is also Deputy Director of the NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI). He trained as a mechanistic enzymologist with Professor John A. Gerlt from the University of Illinois at Urbana-Champaign. As a continuation and elaboration of his interests in enzymology, his current and future research is centered on expanding the multi-faceted interface between enzymology, biological chemistry and synthetic biology, in an area he terms “synthetic enzymology”. In particular, his research is focused on the use of structural and mechanistic enzymological knowledge for protein engineering (exploring, defining and modulating substrate specificities), biocatalysis, therapeutic development (against infectious diseases, cancer and ageing) and bioremediation (towards urban sustainability). His research is closely aligned with industrial needs and solutions, and current industry collaborators include Agilent Technologies, Merck, Illumina, Cimelia Resource Recovery, BD Biosciences, Thermofisher Scientific, Panasonic, Singer Instruments and Wilmar International.