Protein Engineering

Bio-Manufacturing and the Next Wave of Innovation: A Chat With Inscripta’s Richard Fox

Denieka Bean — Thu, 13 Jun 2024 15:59:51 +0000

June 18, 2024

Richard Fox discusses overcoming barriers to progress in synthetic biology and biomanufacturing, looks at where the next wave of innovation will come from, and more.

Industry Interviews

Special Section: Food Engineering

Angelica Dinh — Tue, 05 Sep 2023 18:40:16 +0000

Download the complete 15-page special section.

September

2023

Special Section on Food Engineering: AI-Driven Protein Discovery for Functional Ingredients

Karen Simpson — Mon, 04 Sep 2023 18:58:40 +0000

The global food system needs novel technologies to cope with the increasing demand for protein-rich foods.

September

2023

Functional Proteins Created by Artificial Intelligence

Karen Simpson — Wed, 01 Mar 2023 20:41:58 +0000

March

2023

An artificial intelligence (AI) algorithm can generate protein sequences that work as well or better than natural proteins.

CEP: News Update

Karen Simpson — Wed, 01 Mar 2023 20:41:49 +0000

Nuclear Regulatory Commission Certifies First Small Nuclear Reactor Design; Scientists Find High PFAS Contamination Levels in Freshwater Fish; Functional Proteins Created by Artificial Intelligence; Airport Wastewater Monitoring Tracks the Spread of COVID-19; Studying Sickle Cell Disease with a "Spleen on a Chip"

March

2023

Chemistry Shorts: Driving Reactions

Sonja Bradfield — Wed, 01 Feb 2023 20:28:44 +0000

February 2, 2023

This video is an engaging teaching aid for high school and college students to help directed evolution and how it is being used to develop new tools for plastics recycling and more.

Chemistry Shorts Video Series

Using Porous Protein Crystals to Track Mosquitoes

Karen Simpson — Thu, 29 Dec 2022 15:42:28 +0000

January

2023

DNA "barcodes" embedded in porous protein microcrystals can help track disease-spreading mosquitoes.

AIChE Journal Highlight: Assessing the Extensional Flow of Protein-Excipient Formulations

Karen Simpson — Fri, 02 Dec 2022 04:55:58 +0000

Understanding differences in extensional flow behavior between protein solutions with different excipients can help to design and select better excipients.

December

2022

The Combination of Data-Driven and Physics-Based Modeling with Application in Protein Formulations.

Site Administrator — Tue, 12 Apr 2022 20:30:00 +0000

Conference Presentation

AIChE Spring Meeting and Global Congress on Process Safety

April 12, 2022

With the advent of the data revolution, new avenues open up to integrate data-driven and physics-based modeling. We discuss the application of such...

Catalyzing Commercialization: Redefining Protein Therapeutics with an Expanded Amino Acid Universe

Karen Simpson — Tue, 04 Jan 2022 19:12:44 +0000

Therapeutic proteins are used to treat a wide variety of diseases, yet product stability and unintended immune responses remain significant obstacles.

January

2022

A Tumor-Targeted Cytokine/Antibody Fusion to Stimulate Anti-Cancer Immunity

Site Administrator — Tue, 16 Nov 2021 14:30:00 +0000

Conference Presentation

AIChE Annual Meeting

November 16, 2021

Significance. Interleukin-2 (IL-2) is a pleiotropic cytokine that plays a critical role in T cell function and has been clinically useful in...

Downregulation of the T7 Promoter in E. coli for Enhanced Production of Small Recombinant Spidroins

Site Administrator — Wed, 10 Nov 2021 22:00:00 +0000

Conference Presentation

AIChE Annual Meeting

November 10, 2021

Silk fibroins are some of the most desirable biomaterials due to their unmatched combination of properties that includes, but is not limited to, high...

Using Hyperglycosylation to Immune-Focus Toward Conserved Influenza Hemagglutinin Epitopes

Site Administrator — Wed, 10 Nov 2021 20:48:00 +0000

Conference Presentation

AIChE Annual Meeting

November 10, 2021

A major goal towards next-generation influenza vaccines with broad, protective coverage is to design immunogens that can focus immune responses...

Characterization of Sedimentation and Filtration of Mechanically Labile Protein Crystals on a Small Scale

Site Administrator — Wed, 10 Nov 2021 19:36:00 +0000

Conference Presentation

AIChE Annual Meeting

November 10, 2021

Current research investigates the bulk crystallization for purification or formulation of proteins. Compared to amorph solids, crystalline proteins...

Antibody-Lectin Bispecifics for Targeting Glyco-Immune Checkpoints

Site Administrator — Wed, 10 Nov 2021 19:00:00 +0000

Conference Presentation

AIChE Annual Meeting

November 10, 2021

Cancer immunotherapies, including checkpoint blockade antibodies, represent a breakthrough in cancer treatment with long-term remission observed in...